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The answer lies in The actual fact there are many isoforms of every troponin subunit which might be encoded by unique genes, some of which happen to be expressed selectively in cardiac muscle mass. While TnI and TnT have unique cardiac and skeletal isoforms, they share a typical isoform of TnC: the slow-twitch skeletal muscle mass isoform (ssTnC) (

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The distinctions in AA sequences permitted progress of quantitative assays for cTnI/T. Most cTn assays are non-competitive enzyme-linked immunosorbent assays (ELISA) dependant on the sandwich principle, employing the high specificity and affinity of antibodies.31 The assay is predicated on a seize antibody which binds to a certain epitope of cTn, p

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